During the 11th and 12th centuries, Neive was disputed by various local lords, of which the De Revello stand out. After being awarded the status of Municipality around 1190, the territory of Neive passed from Alba’s sphere of influence to that of rival city Asti. A dispute between Asti and Alba in 1274 resulted in a siege and the castle of Neive was subsequently destroyed in a fit of pique. In 1387, Neive followed Asti and fell into the hands of Giangaleazzo Visconti, remaining under Visconti influence until 1512. A series of scuffles to dominate the town ensued, until it was ceded to the House of Savoy in 1530.
In 1618, Neive was assigned as fief to Count Vittorio Amedeo Dal Pozzo, Marquis of Voghera, who assumed the title of first count of Neive. Neive’s fortunes then followed those of the Savoys until the founding of the Italian Republic.
Though not originally part of the zone of production of Barbaresco, wines from Neive began to gain recognition already in the 19th century, largely as a result of the efforts of enologist Louis Oudart. Invited to Italy at the behest of Marchioness Faletti di Barolo, Oudart modernized the vineyards and cellar techniques in Barolo, wholly transforming production within a few short years. These new techniques were then applied to other wines within the area. Following his success in Barolo, Oudart moved to Neive where he undertook production of fine quality wines.